Pharmacokinetics of bambuterol during oral administration to asthmatic children.

Aims: To investigate dose proportionality, dosing frequency, and ethnic aspects of the pharmacokinetics of bambuterol in asthmatic children, and to discuss the relationship with previous observations in adults.

Methods: Forty-eight children in four different studies completed two double-blind bambuterol treatments each (daily doses of bambuterol hydrochloride): 12 preschool (5 mg x 2 vs 10 mg) and 12 school (10 mg vs 20 mg) Caucasians, 12 preschool (2.5 mg vs 5 mg), and 12 school (10 mg vs 20 mg) Orientals.

[Function of growth hormone in the human energy continuum during physical exertion].

A study has been carried out in 18 healthy sedentary males (controls) and 15 trained handball players. It was programmed two different tests on cycle-ergometer: Test 1 aerobic of progressive increments of load (1 W/kg/3 min) and Test 2 (A) anaerobic (4 W/kg, during 1.5 min) and after resting 10 min.