Publications by authors named "J Quiles-Granado"

Background: Decision tree algorithms, obtained by machine learning, provide clusters of patients with similar clinical patterns by the identification of variables that best merge with a given dependent variable.

Methods: We performed a multicenter registry, with 7 hospitals form Spain, of patients with, or high-risk of having, coronary heart disease (CHD). Elevated Lp(a) was defined as >50 mg/dl.

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Background: Platypnoea-orthodeoxia syndrome (POS) is a rare condition characterized by hypoxaemia and dyspnoea when changing from a recumbent to an upright position. Diagnosis requires a high clinical suspicion and is often underdiagnosed.

Case Summary: We report a case of POS in a 50-year-old woman with dyspnoea and new-onset atrial fibrillation.

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Introduction And Objectives: Hyperkalemia is a growing concern in the treatment of patients with heart failure and reduced ejection fraction because it limits the use of effective drugs. We report estimates of the magnitude of this problem in routine clinical practice in Spain, as well as changes in potassium levels during follow-up and associated factors.

Methods: This study included patients with acute (n=881) or chronic (n=3587) heart failure recruited in 28 Spanish hospitals of the European heart failure registry of the European Society of Cardiology and followed up for 1 year.

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Article Synopsis
  • There is a growing interest in non-invasive methods to detect subclinical atherosclerosis in order to identify patients at high risk for cardiovascular events, particularly in those with diabetes mellitus (DM) and peripheral arterial disease (PAD) during acute coronary syndrome (ACS).
  • A study involving 1,410 ACS patients found that the prevalence of PAD was significantly higher in those with DM (41.5%) compared to those without (30.6%), and patients with both conditions faced more in-hospital cardiac complications and a potential increase in mortality.
  • The combination of DM and PAD serves as a marker for identifying patients at greater risk, while in patients without PAD, DM was linked to three-vessel coronary disease, but this association did not hold in patients
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In the course of the last year, a number of important clinical trials on cardiovascular disease, principally in hypertensive and diabetic patients, have published their results. The findings, some of which were unexpected, have enabled us, in certain instances, to confirm what already we knew about controlling these risk factors, but they have also led to active discussion about well-established topics, such as: To what extent should blood pressure and glycemia levels be reduced in patients with cardiovascular disease? In addition, up-to-date information has become available about treating hypertension with new drugs or new combinations of existing drugs. This article contains a review of all these topics and also summarizes the findings of some observational studies carried out by the working group on hypertension of the Spanish Society of Cardiology that have been reported in the last year.

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