Publications by authors named "J Pujo"

Introduction: French Guiana is a French territory in South America covered by 90% of tropical forest. Despite regular first aid standards training, some of the workers in isolated areas remain untrained in common problems they may encounter. We present here the knowledge assessment of these workers concerning first aid and a new training program.

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  • Lancehead snakes (Bothrops) cause 90% of snakebites in Latin America, prompting a study on the effects of B. atrox venom in male and female mice.
  • The research found that male mice exhibited a lower lethal dose (LD) and more severe physical symptoms from the venom compared to females, particularly via the intraperitoneal injection route.
  • Hematological changes, including a significant drop in total leukocyte levels, were more pronounced in males, indicating a greater susceptibility to B. atrox venom and highlighting the need to consider sex differences in venom studies.
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Introduction: Sexual violence is a major public health issue, including in French Guiana. The feeling of insecurity is significant in this part of France. Sexual violence is an important reason for consultation in forensic and emergency medicine.

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Snakebite envenoming is a high-priority neglected tropical disease and antivenom is the cornerstone of treatment. Antivenom is listed among essential medicines and its access must be considered as a human right. Despite resolutions from various international organizations including the WHO, antivenom remains unavailable, unaffordable, and sometimes not targeted against the specific snake involved.

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  • Functional gastrointestinal disorders (FGIDs) affect over 40% of people globally, causing abdominal pain and altered bowel function, leading to significant economic costs and reduced quality of life.
  • FGIDs have been reclassified as disorders of gut-brain interaction (DGBI), emphasizing the importance of the communication between the gut and the brain in these conditions and their association with mental health issues.
  • The review explores current research on gut microbiome interactions and their role in DGBIs, suggesting that understanding these connections may lead to better treatments for these chronic disorders.
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