Publications by authors named "J Puelles"
As the available treatments for moderate-to-severe atopic dermatitis (AD) expand, understanding patient and physician preferences becomes crucial for informed decision-making. To quantify patient and physician preferences for biologics and oral systemic AD treatment attributes. We conducted a cross-sectional, online discrete choice experiment (DCE) involving 306 AD patients and 206 physicians throughout the United Kingdom and Germany.
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- A patient-focused approach is essential for accurately measuring daily variations in sleep disturbance caused by atopic dermatitis (AD), necessitating validated patient-reported outcome (PRO) measures.
- A study involved literature reviews and interviews with AD patients, leading to the identification of suitable PRO measures, including a single-item sleep disturbance numerical rating scale (SD NRS) and a multi-item Subject Sleep Diary (SSD).
- Results indicated that the SD NRS is a reliable and valid measure of sleep disturbance in adults with AD, effectively capturing the complexity of sleep-related issues associated with the condition.
We described comorbidity, resource utilization, and mortality for patients with prurigo nodularis (PN) using data from the Clinical Practice Research Datalink. Patients with incident PN (2008-2018) were selected and matched to controls. Of 2,416 patients with PN, 2,409 (99.
View Article and Find Full Text PDFIntroduction: Assessing treatment response is key to determining treatment value in atopic dermatitis (AD). Currently, response is assessed using various clinician- or patient-reported measures and response criteria. This variation creates a mismatch of evidence across trials, hindering the ability of clinicians, regulators, and payers to compare the efficacy of treatments.
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