Publications by authors named "J Presneill"
Background: Patients in the intensive care unit (ICU) frequently develop hyperactive delirium, which may be accompanied by behaviour that increases clinical risks to themselves as well as other patients and staff. There is a paucity of evidence to inform the urgent enteral administration of antipsychotic drugs to treat such hyperactive delirium and behavioural disturbances.
Objective: The aim of this study is to test the efficacy and safety of administering enteral olanzapine when compared to quetiapine in critically ill patients with hyperactive delirium.
Missing data and long-term outcomes from nutrition research in the critically ill.
Curr Opin Clin Nutr Metab Care
December 2024
Article Synopsis
- The review highlights the growing importance of using functional outcomes in critical care nutrition research, emphasizing the challenges posed by missing data.
- It points out that ignoring missing data can lead to biased results and suggests proactively estimating the extent and reasons for this missingness.
- The adoption of modern statistical techniques, like multiple imputation and mixed regression models, can enhance the reliability and applicability of research findings in clinical settings.
Background And Aims: Prone positioning is commonly applied to improve gas exchange in mechanically ventilated patients with coronavirus disease 2019 (COVID-19)-related acute respiratory distress syndrome (ARDS). Whilst prone positioning is effective, specific complications may arise. We aimed to assess the prevalence of specific complications related to prone positioning in patients mechanically ventilated for COVID-19-related ARDS.
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- Critically ill patients with traumatic brain injury (TBI) may face extended ICU stays, but the effect of increased enteral nutrition energy delivery on their quality of life is unclear.
- This study aimed to compare the quality of life of TBI survivors on an augmented energy diet (1.5 kcal/ml) versus a routine diet (1.0 kcal/ml) at six months post-admission, while also examining energy delivery, gastrointestinal tolerance, and mortality outcomes.
- Results showed no significant difference in quality of life between the two groups, though those on augmented nutrition received more energy without increased gastrointestinal issues.