Pyrexia of Foreign Origin: Exploring the Impact of Travel History.

Malaria remains a significant global health challenge, particularly in endemic regions of Africa, with being the most virulent species. This case report details the presentation of a 24-year-old Caucasian woman who collapsed at a train station in the United Kingdom after experiencing a week of fever, malaise, abdominal pain, and gastrointestinal symptoms. At emergency care, she was initially resuscitated with intravenous fluids and antipyretics.

CYP1B1-AS1 regulates CYP1B1 to promote Coxiella burnetii pathogenesis by inhibiting ROS and host cell death.

(Cb), the causative agent of Q fever, replicates within host macrophages by modulating immune responses through poorly understood mechanisms. Long non-coding RNAs (lncRNAs) are emerging as critical regulators of inflammation, yet their role in Cb pathogenesis remains largely unexplored. Here, we employed a global transcriptomic approach to identify lncRNAs specific to Cb infection in THP-1 derived macrophages, compared to 15 other microbial infections.

Predictive value of clinico-radiological variables in the management of suspected foreign body aspiration in children: A ten-year retrospective cohort study.

Background: Definite history is not always present in children with foreign body aspiration (FBA), hence necessitating a high index of suspicion.

Objective: To assess the predictive value of clinico-radiological variables among children presenting with features of suspected FBA and to document their course in a tertiary care teaching hospital.

Materials And Methods: In this retrospective observational study, we included children aged below 15 years presenting with clinical features of suspected FBA.

Indigenous-led struggles for health justice in the context of the climate emergency: insights from Guatemala.

This practice paper reflects on an ongoing Participatory Action Research project that combines community-engaged methods, national data analysis and advocacy to support community-based emergency response to extreme weather events in 16 Indigenous communities in Alta Verapaz province, Guatemala. Our work points to a worrying predicament experienced in climate-affected areas, where some populations face a dangerous confluence of climate vulnerability, social exclusion and state abandonment that imperils human health. Indigenous communities in Alta Verapaz are often particularly vulnerable to health impacts from climate-driven extreme weather events, a reality compounded by the historical and contemporary ways the state marginalises them.