Factor V Leiden and prothrombin gene G 20210 A variant in children with ischemic stroke.

Objective: To investigate if the factor V Leiden mutation (F-V-LM) and/or the prothrombin gene G 20210 A variant (P-G20210A-V) are risk factors for acute stroke in Austrian children.

Patients: 33 children with acute ischemic stroke documented by computer tomography and/or magnetic resonance imaging of the brain were enrolled in an open multicenter survey.

Results: 6/33 children had F-V-LM (5 heterozygous, 1 homozygous).