Changes in microcirculation following transcatheter aortic valve implantation in patients with stable coronary artery disease.

Background: Few studies have assessed coronary physiology in the setting of coronary artery disease (CAD) with severe aortic stenosis (AS). Fractional flow reserve (FFR) to guide revascularization in such patients is not validated.

Aims: We describe changes in coronary physiology in this population before and after transcatheter aortic valve implantation (TAVI).

Pelvic sheet binders: Are doctors placing them in the correct position?

Introduction: Unstable pelvic fractures cause significant bleeding, morbidity, and mortality. Commercially available Pelvic Circumferential Compression Devices (PCCDs) are used in the initial resuscitation and management of these cases. In the trauma-burdened, resource limited setting of Southern Africa, the available alternative is a pelvic sheet binder (PSB).

Solar Ultraviolet Radiation Exposure Among Opencast Miners in Namibia with the Use of Electronic Dosimeters: A Feasibility Study.

The lack of information on exposure of opencast mineworkers to solar ultraviolet radiation, a group I carcinogen, was addressed. The feasibility of using electronic dosimeters in the determination of exposure to solar ultraviolet radiation was investigated. The objective of the study was to determine the feasibility of measuring the occupational exposure of opencast mineworkers to solar ultraviolet radiation using electronic dosimeters.

A conceptual framework for psychiatric nurses to facilitate medication compliance among adults living with depression.

Background:  Medication non-compliance is a significant healthcare issue that is widespread. Extensive research has identified factors that contribute to medication non-compliance in different healthcare settings. As a result, there was a need to develop a conceptual framework to facilitate medication compliance among adults living with depression.

Machine Learning to Predict Interim Response in Pediatric Classical Hodgkin Lymphoma Using Affordable Blood Tests.

Purpose: Response assessment of classical Hodgkin lymphoma (cHL) with positron emission tomography-computerized tomography (PET-CT) is standard of care in well-resourced settings but unavailable in most African countries. We aimed to investigate correlations between changes in PET-CT findings at interim analysis with changes in blood test results in pediatric patients with cHL in 17 South African centers.

Methods: Changes in ferritin, lactate dehydrogenase (LDH), erythrocyte sedimentation rate (ESR), albumin, total white cell count (TWC), absolute lymphocyte count (ALC), and absolute eosinophil count were compared with PET-CT Deauville scores (DS) after two cycles of doxorubicin, bleomycin, vinblastine, and dacarbazine in 84 pediatric patients with cHL.