Publications by authors named "J Pizarro-Cerda"

Cold atmospheric plasma (CAP) is a promising complement to tissue repair and regenerative medicine approaches. CAP has therapeutic potential in infected cutaneous wounds by mechanisms which remain enigmatic. Here, CAP is shown to activate phagocyte NADPH oxidase complex NOX2.

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Background: Plague, a zoonotic disease caused by Yersinia pestis, was responsible for 3 historical human pandemics that killed millions of people. It remains endemic in rodent populations in Africa, Asia, North America, and South America but human plague is rare in most of these locations. However, human plague is still highly prevalent in Madagascar, which typically records a significant part of all annual global cases.

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Bloodstream infection is a major public health concern associated with high mortality and high healthcare costs worldwide. Bacteremia can trigger fatal sepsis whose prevention, diagnosis, and management have been recognized as a global health priority by the World Health Organization. Additionally, infection control is increasingly threatened by antimicrobial resistance, which is the focus of global action plans in the framework of a One Health response.

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Article Synopsis
  • Enteric yersiniosis is a common food-borne illness in Europe, primarily monitored in France by the Yersinia National Reference Laboratory, which has been using whole genome sequencing (WGS) since 2017 to analyze isolates.
  • From 2017 to 2021, a total of 7,642 strains were characterized, revealing the majority (87.2%) were from the most common pathogenic lineage (lineage 4).
  • A new typing method called core genome Multilocus Sequence Typing (cgMLST) was developed to enhance surveillance, resulting in the identification of 419 clusters of pathogenic isolates, which aids in understanding outbreaks and cases more effectively.
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