Preliminary Evidence for an Association Between Variants of the Catechol-O-Methyltransferase (COMT) Gene and Premature Ejaculation.

Background: Studies have suggested that dopamine plays a role in the neurobiological mechanism that triggers ejaculation, leading scientists to hypothesize that dopamine-related genetic polymorphisms could contribute to symptoms of premature ejaculation (PE).

Aim: To investigate associations between dopamine receptor and catechol-O-methyltransferase (COMT; an enzyme involved in the catabolism of dopamine) gene-linked polymorphisms and PE.

Methods: PE status in patient groups was determined by clinical diagnosis performed by a physician specializing in sexual medicine.

Mother's marital satisfaction associated with the quality of mother-father-child triadic interaction.

Low marital satisfaction has been shown to be a risk factor for early parenthood and parent-child relationship problems (Erel & Burman, ; McHale, ). The aim of this study was to assess how parental reports of marital satisfaction related to family alliance and coordination in the observed triadic interaction. The study group included 120 families.

A Longitudinal Analysis of Premature Ejaculation Symptoms Raises Concern Regarding the Appropriateness of a "Lifelong" Subtype.

Unlabelled: Premature ejaculation (PE) is divided into acquired and lifelong subtypes, with the implication that the latter is chronic. This longitudinal study included data for untreated respondents from a population-based sample (sample 1) and a sample of patients diagnosed with lifelong PE (sample 2). About half of the respondents who at time 1 fulfilled the most important diagnostic criterion for lifelong PE (≤1minute ejaculation latency) no longer did so at time 2.

Intercorrelations and developmental pathways of mothers' and fathers' loneliness during pregnancy, infancy and toddlerhood--STEPS study.

Our aim was to study the inter-correlations and developmental pathways of mothers' and fathers' social and emotional loneliness during pregnancy (20th pregnancy week), infancy (child aged 8 months), and early childhood (child aged 18 months). Moreover, we aimed to study whether mothers and fathers who have different developmental profiles (identified by latent growth curve mixture models) differ in their experiences of marital dissatisfaction (RDAS), social phobia (SPIN) and depression (BDI) during pregnancy. Both mothers' social and emotional loneliness and fathers' social and emotional loneliness were highly stable, and within individuals these loneliness factors were strongly correlated.