Patterns of partisan toxicity and engagement reveal the common structure of online political communication across countries.

Existing studies of political polarization are often limited to a single country and one form of polarization, hindering a comprehensive understanding of the phenomenon. Here we investigate patterns of polarization online across nine countries (Canada, France, Germany, Italy, Poland, Spain, Turkey, UK, USA), focusing on the structure of political interaction networks, the use of toxic language targeting out-groups, and how these factors relate to user engagement. First, we show that political interaction networks are structurally polarized on Twitter (currently X).

Nurse Burnout and Patient Safety, Satisfaction, and Quality of Care: A Systematic Review and Meta-Analysis.

Importance: Occupational burnout syndrome is characterized by emotional exhaustion, depersonalization, and a diminished sense of personal accomplishment and is prevalent among nurses. Although previous meta-analyses have explored the correlates of nurse burnout, none have estimated their association with health care quality and safety and patient morbidity and mortality.

Objective: To evaluate the magnitude and moderators of the association between nurse burnout and patient safety, patient satisfaction, and quality of care.

KAT2A and KAT2B prevent double-stranded RNA accumulation and interferon signaling to maintain intestinal stem cell renewal.

Histone acetyltransferases and are paralogs highly expressed in the intestinal epithelium, but their functions are not well understood. In this study, double knockout of murine genes in the intestinal epithelium was lethal, resulting in robust activation of interferon signaling and interferon-associated phenotypes including the loss of intestinal stem cells. Use of pharmacological agents and sterile organoid cultures indicated a cell-intrinsic double-stranded RNA trigger for interferon signaling.

An up to thirty-year retrospective study on the success and survival of single unit and splinted implant-supported crowns in a dental school setting.

Statement Of Problem: Studies investigating the survival of implant-supported crowns provided in a dental school setting are sparse.

Purpose: The purpose of this retrospective study was to evaluate the success and reasons for failure of single unit and splinted implant-supported crowns provided in a dental school.

Material And Methods: Using the axiUm dental management software program and paper charts, all single unit and splinted implant-supported crowns provided between September 1989 and January 2020 were included for evaluation.