Publications by authors named "J Penninkhof"
Evaluation of artificial intelligence-based autosegmentation for a high-performance cone-beam computed tomography imaging system in the pelvic region.
Phys Imaging Radiat Oncol
January 2025
Background And Purpose: A novel ring-gantry cone-beam computed tomography (CBCT) imaging system shows improved image quality compared to its conventional version, but its effect on autosegmentation is unknown. This study evaluates the impact of this high-performance CBCT on autosegmentation performance, inter-observer variability, contour correction times and delineation confidence, compared to the conventional CBCT.
Materials And Methods: Twenty prostate cancer patients were enrolled in this prospective clinical study.
Purpose: To contrast breast radiation exposure from chest radiotherapy in 2006-2021 with 1965-1997, and to compare breast cancer (BC) risk 25 years after treatment predicted by two models.
Methods: Radiation dose distributions to the breast from 101 chest radiotherapies given 2006-2021 for Hodgkin lymphoma (HL) or other lymphoma in one German and two Dutch hospitals were compared with doses received by 505 Dutch HL patients treated 1965-1997 and sampled into a nested case-control study, weighted to represent a HL patient cohort. Dose-volume histograms, mean dose and doses to 10 breast segments were evaluated.
Article Synopsis
- The HyperSight high-performance CBCT imaging system provides better Hounsfield unit accuracy and image quality for treatment planning in cancer patients.
- A study compared dose calculation accuracy between HyperSight CBCT and traditional planning CT in prostate and lung cancer cases, evaluating various dose distribution parameters.
- Results showed HyperSight CBCT yielded accurate dose calculations for prostate patients, but breathing motion significantly affected accuracy for lung cancer patients.*
Background And Purpose: A novel Cone-Beam Computed Tomography (CBCT) named HyperSight provides superior CBCT image quality compared to conventional ring gantry CBCT imaging, and it is suitable for dose calculations for prostate cancer, but it comes with considerable additional costs. The aim of this study was to determine the added value of HyperSight CBCT imaging compared to conventional CBCT imaging in terms of organ visibility in the male pelvic region.
Materials And Methods: Twenty prostate cancer patients were included in this prospective clinical study.
Background And Purpose: To evaluate the performance of automated surface-guided gating for left-sided breast cancer with DIBH and VMAT.
Materials And Methods: Patients treated in the first year after introduction of DIBH with VMAT were retrospectively considered for analysis. With automated surface-guided gating the beam automatically switches on/off, if the surface region of interest moved in/out the gating tolerance (±3 mm, ±3°).