Publications by authors named "J Pendergast"
Objective: Fear of Aversive Consequences (FOAC), such as choking or vomiting, is an important associated feature of Avoidant/Restrictive Food Intake Disorder (ARFID). However, the manifestation of FOAC in young children is poorly understood. This study aimed to describe the fears of children with ARFID symptoms and examine the concordance between parent and child ratings of fear.
View Article and Find Full Text PDFOlder age is linked with poorer self-care in the chronic kidney disease (CKD) setting. Informal health supporters (family members and friends) are critical sources of self-care support, but much remains unclear about the characteristics and implications of received support among this patient population. We examined how received self-care support (amount and type) related to positive (CKD management self-efficacy) and negative (depressive symptoms) psychosocial health correlates of self-care in 536 adults aged 65 years and older with non-dialysis-dependent CKD.
View Article and Find Full Text PDFArticle Synopsis
- The study examines the effects of prescribing multiple psychoactive medications, specifically gabapentinoids alongside other potentially inappropriate medications (PPIMs), in patients undergoing dialysis.
- It found that coprescribing these medications significantly increases the risk of altered mental status (AMS) and falls, especially in patients with varying levels of frailty.
- Results indicate that frailty influences the severity of these risks, with the highest hazard for AMS and falls observed in patients with severe frailty receiving multiple psychoactive prescriptions.
Article Synopsis
- The study investigates how patient-directed educational materials can help clinicians reduce unnecessary prescriptions for specific medication groups, notably proton pump inhibitors and high-risk diabetes treatments.
- Conducted across three VA medical centers, the trial involved 5071 patients and compared an intervention cohort receiving educational brochures to a control group from the previous year.
- Results showed a higher deprescribing rate among the intervention group (29.5%) compared to the control group (25.8%), indicating that the educational intervention positively affected medication management practices.
The Estrous Cycle Coordinates the Circadian Rhythm of Eating Behavior in Mice.
J Biol Rhythms
October 2024
The estrous cycle regulates rhythms of locomotor activity, body temperature, and circadian gene expression. In female mice, activity increases on the night of proestrus, when elevated estrogens cause ovulation. Exogenous estradiol regulates eating behavior rhythms in female mice fed a high-fat diet, but it is unknown whether endogenous estrogens regulate eating rhythms.
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