Fluid overload (FO) with coincident acute kidney injury has been associated with increased mortality. However, it is unclear whether FO is an independent determinant of mortality for disease severity. We aimed to explore whether the development of fluid balance (FB) during the first 72 h of continuous renal replacement therapy (CRRT) is independently associated with hospital mortality.
View Article and Find Full Text PDFWe report an outbreak of invasive pneumococcal disease and pneumococcal pneumonia among shipyard workers, in Turku, Southwest Finland. In total, 31 confirmed and six probable cases were identified between 3 May and 28 November 2019. serotypes 12F, 4 and 8 were isolated from blood cultures of 25 cases.
View Article and Find Full Text PDFTheoretical, numerical, and experimental methods are presented for multiple scattering of light in macroscopic discrete random media of densely-packed microscopic particles. The theoretical and numerical methods constitute a framework of Radiative Transfer with Reciprocal Transactions (RT). The RT framework entails Monte Carlo order-of-scattering tracing of interactions in the frequency space, assuming that the fundamental scatterers and absorbers are wavelength-scale volume elements composed of large numbers of randomly distributed particles.
View Article and Find Full Text PDFWe consider the scattering and absorption of light in discrete random media of densely packed spherical particles. In what we term "radiative transfer with reciprocal transactions" (RT), we introduce a volume element of the random medium, derive its scattering and absorption characteristics using the superposition T-Matrix method (STMM), and compute its frequency-domain incoherent volume-element scattering characteristics. Using an order-of-scattering approach, we then compute a numerical Monte Carlo solution for the scattering problem with an exact treatment of the interaction between two volume elements.
View Article and Find Full Text PDFObjective: To investigate brain amyloid pathology in a dementia-risk population defined as cardiovascular risk factors, aging, and dementia risk (CAIDE) score of at least 6 but with normal cognition and to examine associations between brain amyloid load and cognitive performance and vascular risk factors.
Methods: A subgroup of 48 individuals from the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) main study participated in brain C-Pittsburgh compound B (PiB)-PET imaging, brain MRI, and neuropsychological assessment at the beginning of the study. Lifestyle/vascular risk factors were determined as body mass index, blood pressure, total and low-density lipoprotein cholesterol, and glucose homeostasis model assessment.