Publications by authors named "J Pearse"

Paramos, unique and biodiverse ecosystems found solely in the high mountain regions of the tropics, are under threat. Despite their crucial role as primary water sources and significant carbon repositories in Colombia, they are deteriorating rapidly and garner less attention than other vulnerable ecosystems like the Amazon rainforest. Their fertile soil and unique climate make them prime locations for agriculture and cattle grazing, often coinciding with economically critical deposits such as coal which has led to a steady decline in paramo area.

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Objective: To assess the impact of the Health Care Homes (HCH) primary health care initiative on quality of care and patient outcomes.

Design, Setting: Quasi-experimental, matched cohort study; analysis of general practice data extracts and linked administrative data from ten Australian primary health networks, 1 October 2017 - 30 June 2021.

Participants: People with chronic health conditions (practice data extracts: 9811; linked administrative data: 10 682) enrolled in the HCH 1 October 2017 - 30 June 2019; comparison groups of patients receiving usual care (1:1 propensity score-matched).

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Article Synopsis
  • Fluorescent proteins (FPs) are widely used in research, but their natural roles are not well understood; this study focuses on intertidal sea anemones and how FPs contribute to color variation and response to oxidative stress.
  • The research highlights that a specific green color morph of FP is linked to different alleles of a single gene, which enhances both color vibrancy and antioxidant capacity.
  • By modeling the amino acids involved, the study proposes that the antioxidant properties of FPs are influenced by their molecular surface charge, showing how a single FP can serve multiple functions in nature.
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Background: Early intervention in cerebral palsy could improve motor outcome but is only possible following early identification of those affected. There is a need for training of healthcare professionals (HCPs) in early detection of atypical motor development. We developed a video-based e-learning course - Training in Early Detection for Early Intervention (TEDEI) - to address this need.

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Aim: To determine whether a wrist-worn triaxial accelerometer-based device and software (including smartphone application), incorporating feedback, is feasible, acceptable, and can lead to increased affected upper limb use during everyday activities in children with unilateral cerebral palsy (UCP).

Methods: Mixed methods proof of concept study. Children aged 8-18 years with UCP; age-matched typically developing controls ("Buddies"), therapists.

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