Epilepsy in the pediatric and adolescent populations is a devastating condition where individuals are prone to recurrent epileptic seizures or changes in behavior or movement that is the direct result of a primary change in the electrical activity in the brain. Although many children with epilepsy will have seizures controlled with antiseizure medications (ASMs), a large percentage of patients are refractory to drug therapy and may consider initiating a ketogenic diet. The term Ketogenic Diet or Ketogenic Diet Therapy (KDT) refers to any diet therapy in which dietary composition results in a ketogenic state of human metabolism.
View Article and Find Full Text PDFObjective: To evaluate serum levels of liver enzymes and bilirubin before and after six cycles of use of a triphasic oral contraceptive containing 35 micrograms of ethinylestradiol and 180/215/250 micrograms of norgestimate (Pramino, Janssen-Cilag).
Design: A prospective, open-label, non-comparative, multicentric phase IV study.
Setting: Department of Obstetrics and Gynaecology, 1st Medical Faculty, Charles University, Prague.
Objective: To assess the frequency of factor V Leiden in oral contraceptive users and to define possible anamnestic data that could predict the presence of factor V Leiden.
Methods: Between 1997 and 1998, 583 users of oral estrogen-progestin contraceptives with no history of thrombotic disease were examined. Factor V Leiden was assessed by PCR after isolating DNA from a peripheral venous blood sample.
Objective: Prediction of complexion changes in users of triphasic oral contraceptive containing norgestimate.
Design: Analysis of data from a prospective multicentre open study.
Setting: Department of Obstetrics and Gynaecology, Charles University, Prague.