Publications by authors named "J Pascal Gollin"
A graph is said to be -, where is the minor relation between graphs, if whenever is a graph with for all , then one also has , where is the disjoint union of many copies of . A well-known conjecture of Andreae is that every locally finite connected graph is -ubiquitous. In this paper we give a sufficient condition on the structure of the ends of a graph which implies that is -ubiquitous.
View Article and Find Full Text PDFThe epicardium, the outermost layer of the heart, is an important regulator of cardiac regeneration. However, a detailed understanding of the crosstalk between the epicardium and myocardium during development requires further investigation. Here, we generated three models of epicardial impairment in zebrafish by mutating the transcription factor genes tcf21 and wt1a, and ablating tcf21+ epicardial cells.
View Article and Find Full Text PDFERK phosphorylation is dependent on cell adhesion in a subset of pediatric sarcoma cell lines.
Biochim Biophys Acta Mol Cell Res
August 2022
Article Synopsis
- Osteosarcoma (OS) and Pax-Foxo1 fusion negative rhabdomyosarcoma (FN-RMS) are serious pediatric cancers known for their poor outcomes, especially in advanced stages, with a focus on the role of actin binding proteins in worsening prognosis.
- The study investigates how integrin adhesion complexes (IACs) and actin dynamics influence ERK activation in different cell lines from OS and FN-RMS, revealing varied adhesion-dependent responses between the two cancer types.
- Findings indicate that ERK phosphorylation is not consistently affected by adhesion in OS cells, while in FN-RMS, adhesion boosts ERK activation and points to distinct mechanisms of cell signaling that differ from existing models observed in other cancers.