Publications by authors named "J Parvizi"

Article Synopsis
  • The human microbiome consists of microorganisms like bacteria and fungi that impact health, with imbalances (dysbiosis) linked to diseases such as asthma and obesity.
  • Current research is exploring how the gut microbiome specifically affects joint health and diseases like osteoarthritis through inflammatory responses triggered by dysbiosis.
  • The review aims to enhance our understanding of the microbiome's role in disease and emphasizes the need for further studies on the joint microbiome's impact on conditions like periprosthetic joint infection.
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In general, periprosthetic joint infection (PJI) is regarded as one of the most common complications of total joint arthroplasty (TJA) and may lead to surgical failure, revision surgery, amputation or death. Nowadays, PJI has become a global health concern, which brings a great burden to public healthcare. In addition, there are still obstacles to achieve high success rates in the prevention, diagnosis and treatment of PJI.

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Background: Periprosthetic joint infection (PJI) is a severe complication following total joint arthroplasty. This study aimed to investigate the dynamics of synovial fluid markers following single-stage exchange arthroplasty or debridement, combined with antibiotics and implant retention with topical antibiotic infusion for PJI.

Methods: This retrospective study analyzed patient records at a tertiary hospital from March 1, 2018, to May 1, 2023.

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Article Synopsis
  • The study explores a new method for mapping personalized seizure pathways in the thalamus using multidimensional stereotactic electroencephalography (sEEG).
  • It includes innovative techniques for sampling various thalamic nuclei with minimal electrodes, including multilead orthogonal and long-axis trajectories.
  • The methods were tested in 34 patients without any complications, highlighting their effectiveness for better understanding and treating epilepsy through targeted thalamic sampling.
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