A magnetic particle time-of-flight (MagPTOF) diagnostic for measurements of shock- and compression-bang time at the NIF (invited).

A magnetic particle time-of-flight (MagPTOF) diagnostic has been designed to measure shock- and compression-bang time using D(3)He-fusion protons and DD-fusion neutrons, respectively, at the National Ignition Facility (NIF). This capability, in combination with shock-burn weighted areal density measurements, will significantly constrain the modeling of the implosion dynamics. This design is an upgrade to the existing particle time-of-flight (pTOF) diagnostic, which records bang times using DD or DT neutrons with an accuracy better than ±70 ps [H.

Genetic instability in microsatellite sequences in prostate-cancer.

Mutations in microsatellite sequences, especially expansion in the number of di- and trinucleotide repeats, have been implicated as the cause of several heritable disorders, including fragile X syndrome and myotonic dystrophy. We examined the possibility that a similar mutation mechanism might be involved in human prostate cancer. Our findings indicate that mutations in microsatellite sequences are frequent in prostate cancer.