Publications by authors named "J Papuga"

The turning process remains one of the most widely used manufacturing methods in the industry due to its high flexibility and production rates. Despite being an extensively used technique, the impact of this machining process on the surface integrity of the components has not yet been resolved in the literature, although it is well known that it can have a major influence on their final life. With the aim of providing new insights in the field, an extensive experimental campaign was designed on a 42CrMo4 quenched and tempered steel (in the following 42CrMo4+QT) using the response surface method.

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An unmet need exists for patients with relapsed/refractory (R/R) follicular lymphoma (FL) and high-risk disease features, such as progression of disease within 24 months (POD24) from first-line immunochemotherapy or disease refractory to both CD20-targeting agent and alkylator (double refractory), due to no established standard of care and poor outcomes. Chimeric antigen receptor (CAR) T cell therapy is an option in R/R FL after two or more lines of prior systemic therapy, but there is no consensus on its optimal timing in the disease course of FL, and there are no data in second-line (2L) treatment of patients with high-risk features. Lisocabtagene maraleucel (liso-cel) is an autologous, CD19-directed, 4-1BB CAR T cell product.

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The paper deals with an approximate method for calculating elastic-plastic stresses and strains on the surface of notched samples. The method is based on the Abdel-Karim-Ohno cyclic plasticity model. The plane stress condition is considered within the evaluation.

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The paper discusses one of the key features in the multiaxial fatigue strength evaluation-the procedure in which the stress path is analyzed to provide relevant measures of parameters required by multiaxial criteria. The selection of this procedure affects the complete equivalent stress derived for any multiaxial load combinations. Three major concepts-the minimum circumscribed circle, minimum circumscribed ellipse, and moment of inertia methods-are described.

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