Publications by authors named "J Pantoglou"
Article Synopsis
- This study examines how patient care differs among general practitioners in Upper Austria, focusing on various organizational forms like single practices, group practices, and primary health care units.
- Data collection involved analyzing patient demographics, prescription patterns, and service offerings, revealing that single practices tend to prescribe more medications for chronic conditions while group practices are more common in populated areas.
- The findings highlight inconsistencies in documenting patient visit reasons and emphasize the importance of standardized practices for better outbreak management in outpatient medicine.
Background: A cluster-Randomised Controlled Trial evaluation of the impact of the Community Health Clubs (CHCs) in the Community Based Environmental Health Promotion Programme in Rwanda in 2015 appeared to find little uptake of 7 hygiene indicators 1 year after the end of the intervention, and low impact on prevention of diarrhoea and stunting.
Methods: Monitoring data was revisited through detailed community records with all the expected inputs, outputs and external determinants analysed for fidelity to the research protocol. Five household inventory observations were taken over a 40-month period including 2 years after the end of the cRCT in a random selection of the 50 intervention CHCs and data compared to that of the trial.
Genome editing is the introduction of directed modifications in the genome, a process boosted to therapeutic levels by designer nucleases. Building on the experience of ex vivo gene therapy for severe combined immunodeficiencies, it is likely that genome editing of haematopoietic stem/progenitor cells (HSPC) for correction of inherited blood diseases will be an early clinical application. We show molecular evidence of gene correction in a mouse model of primary immunodeficiency.
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