Publications by authors named "J Panotopoulos"
Soft tissue tumor imaging in adults: European Society of Musculoskeletal Radiology-Guidelines 2024: imaging immediately after neoadjuvant therapy in soft tissue sarcoma, soft tissue tumor surveillance, and the role of interventional radiology.
Eur Radiol
December 2024
Article Synopsis
- The ESSR updated its 2015 consensus on soft tissue tumor imaging due to advancements in technology and updated classifications.
- A panel of 46 radiologists from 12 European countries used a validated Delphi method to reach consensus on imaging strategies, resulting in high agreement on 47 statements.
- Key findings highlight that MRI is preferred for monitoring soft tissue sarcomas, with chest CT recommended for assessing metastasis and interventional radiology playing a role in treating specific cases.
Soft tissue tumor imaging in adults: whole-body staging in sarcoma, non-malignant entities requiring special algorithms, pitfalls and special imaging aspects. Guidelines 2024 from the European Society of Musculoskeletal Radiology (ESSR).
Eur Radiol
January 2025
Objectives: The revised European Society of Musculoskeletal Radiology (ESSR) consensus guidelines on soft tissue tumor imaging represent an update of 2015 after technical advancements, further insights into specific entities, and revised World Health Organization (2020) and AJCC (2017) classifications. This second of three papers covers algorithms once histology is confirmed: (1) standardized whole-body staging, (2) special algorithms for non-malignant entities, and (3) multiplicity, genetic tumor syndromes, and pitfalls.
Materials And Methods: A validated Delphi method based on peer-reviewed literature was used to derive consensus among a panel of 46 specialized musculoskeletal radiologists from 12 European countries.
Objectives: Early, accurate diagnosis is crucial for the prognosis of patients with soft tissue sarcomas. To this end, standardization of imaging algorithms, technical requirements, and reporting is therefore a prerequisite. Since the first European Society of Musculoskeletal Radiology (ESSR) consensus in 2015, technical achievements, further insights into specific entities, and the revised WHO-classification (2020) and AJCC staging system (2017) made an update necessary.
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- * Conducted on 158 patients treated at the Medical University of Vienna, the research utilized statistical methods like Kaplan-Meier curves and Cox proportional hazard models to analyze data collected from 1994 to 2021.
- * Findings showed that higher fibrinogen levels were associated with poorer overall survival rates, with a significant hazard ratio indicating increased mortality risk as fibrinogen levels rose; this remained true even after adjusting for tumor stage.
Article Synopsis
- * It highlights the typical appearances of common tumors, notes that many swellings are non-cancerous, and emphasizes the rarity of sarcomas, which can mimic benign conditions, particularly synovial sarcoma.
- * The importance of adhering to diagnostic guidelines and collaborating with specialized tumor centers for effective post-treatment monitoring and managing potential complications is stressed.