Methamphetamine-associated cardiomyopathy continues to grow within the United States. Although initiation of guideline-directed medical therapy and cessation of methamphetamine are cornerstones of therapy, many barriers to guideline-directed medical therapy use exist for patients with methamphetamine-associated cardiomyopathy. This paper presents a case series of patients who demonstrated profound clinical and echocardiographic improvement with engagement in a community heart failure program paired with the use of alarmed pill containers to target medication adherence.
View Article and Find Full Text PDFBackground: While the incidence of pregnancy has increased among individuals with adult CHD, little has been described about considerations and experiences of patients with adult CHD regarding pregnancy.
Objective: We aimed to explore patients' motivations, concerns, and decision-making processes regarding pregnancy.
Methods: In April 2019-January 2020, we conducted in-depth telephone interviews with patients (n = 25) with simple, moderate, or complex adult CHD, who received prenatal care at the University of Washington during 2010-2019 and experienced a live birth.
Background: Clostridium thermocellum is a promising candidate for consolidated bioprocessing of lignocellulosic biomass to ethanol. The low ethanol tolerance of this microorganism is one of the remaining obstacles to industrial implementation. Ethanol inhibition can be caused by end-product inhibition and/or chaotropic-induced stress resulting in increased membrane fluidization and disruption of macromolecules.
View Article and Find Full Text PDFAim: The rectovaginal fistula (RVF) is relatively uncommon and by clinical manifestations grave illness. The surgery treatment of RVF is extremely demanding and represents the subject of frustration for many surgeons. Miscellaneous etiology of RVF and various heights of fistula in a rectovaginal septum are crucial for the choice of surgical procedure.
View Article and Find Full Text PDFVaccination remains the leading strategy against COVID-19 worldwide. BNT162b2 is among the first licensed vaccines with high effectiveness. However, the role of antibody and cell immunity response monitoring after vaccination remains unclear.
View Article and Find Full Text PDF