Long-term oncologic outcomes of robot-assisted versus conventional open esophagectomy for esophageal cancer: Propensity-score matched anaylsis.

Background: This study aimed to compare the long-term oncologic outcomes of robot-assisted minimally invasive esophagectomy (RAMIE) with those of conventional open esophagectomy (OE) for esophageal cancer.

Methods: Between January 2006 and December 2021, 1745 consecutive patients underwent esophagectomy for esophageal cancer at Asan Medical Center, Korea. Among them, we retrieved 1133 patients (mean age 63.

Flat-Band Electronic Bipolarity in a Janus and Kagome van der Waals Semiconductor NbTeI.

Janus materials, a novel class of materials with two faces of different chemical compositions and electronic polarities, offer significant potential for various applications with catalytic reactions, chemical sensing, and optical or electronic responses. A key aspect for such functionalities is face-dependent electronic bipolarity, which is usually limited by the chemical distinction of terminated surfaces and has not been exploited in the semiconducting regime. Here, it is showed that a Janus and Kagome van der Waals (vdW) material NbTeI has ferroelectric-like coherent stacking of the Janus layers and hosts strong electronic bipolar states in the semiconducting regime.

Anticancer effect of a single-chain variable fragment against pro-matrix metalloproteinase-7 in colon cancer.

Disrupting the interaction between matrix metalloproteinase-7 (MMP-7) and syndecan-2 (SDC-2) can yield anticancer effects in colon cancer cells. Here, a single-chain variable fragment (scFv) targeting the pro-domain of MMP-7 was generated as a potential candidate anticancer agent. Among the generated scFvs, those designated 1B7 and 1C3 showed the strongest abilities to inhibit the ability of MMP-7 pro-domain to directly interact with SDC-2 in vitro and decrease the cancer activities of human HT29 colon adenocarcinoma cells.

Successful Treatment of Growing Skull Fracture That Developed Only 3 Weeks After Injury: A Case Report.

A growing skull fracture (GSF) is a fracture that gradually widens as the arachnoid membrane or brain parenchyma herniates into the fractured space in a skull fracture accompanied by dural injury. GSF has a good prognosis if diagnosed early and treated surgically. However, it is generally a chronic complication with low incidence, making diagnosis difficult.