Publications by authors named "J P Werba"
Making timely management decisions is often hindered by uncertainty. Monitoring reduces two key types of uncertainty. First, it serves to reduce structural uncertainty of how the system works and provides support for expectations of how a system works.
View Article and Find Full Text PDFEstimating distributions for cryptic and highly range-restricted species induces unique challenges for species distribution modeling. In particular, bioclimatic covariates that are typically used to model species ranges at regional and continental scales may not show strong variation at scales of 100s and 10s of meters. This limits both the likelihood and usefulness of correlated occurrence to data typically used in distribution models.
View Article and Find Full Text PDFAtherosclerotic cardiovascular diseases remain the main cause of mortality worldwide, due to a poor control of modifiable risk factors for atherosclerosis. High levels of low-density lipoprotein cholesterol represent the most relevant actor in the development of atherosclerotic cardiovascular diseases, as well as the main target of prevention strategies. Although lipid-lowering treatments were shown to be effective for cardiovascular prevention, several barriers (e.
View Article and Find Full Text PDFArticle Synopsis
- Takotsubo cardiomyopathy (TTS) is shown to have long-term effects on the hemostatic system, with patients exhibiting accelerated clot formation and higher levels of platelet activation even years after the initial event.
- In a study of women with TTS, results indicated significant differences in clotting parameters compared to both healthy controls and those with coronary artery disease (CAD), pointing to unique pathophysiological changes in TTS.
- Findings suggest that the persistent alterations in the hemostatic system in TTS patients may contribute to recurrent events, highlighting the need for tailored antiplatelet therapy to mitigate adverse outcomes.
Rationale and design of the CV-PREVITAL study: an Italian multiple cohort randomised controlled trial investigating innovative digital strategies in primary cardiovascular prevention.
BMJ Open
July 2023
Introduction: Prevention of cardiovascular disease (CVD) is of key importance in reducing morbidity, disability and mortality worldwide. Observational studies suggest that digital health interventions can be an effective strategy to reduce cardiovascular (CV) risk. However, evidence from large randomised clinical trials is lacking.
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