Crescentic proximal metatarsal osteotomy for moderate to severe hallux valgus: a mean 12.2 year follow-up study.

The senior author's (R.C.) first 25 patients (37 feet) treated with a combination proximal crescentic osteotomy and distal soft-tissue reconstruction made up the patient cohort.

Immunocytochemical localization of glutathione S-transferase Yo subunit in the rat testis and epididymis.

The glutathione S-transferases (GSTs) are a family of isozymes that catalyze the conjugation of glutathione with electrophiles. These proteins exist as homo- or heterodimers and are separated into five classes (alpha, mu, pi, theta, and sigma). In the present study, the distribution of the GST Yo subunit, a member of the mu family, was examined immunocytochemically in the adult rat testis and epididymis using both light microscopy (LM) and electron microscopy (EM).

Immunocytochemical localization of the Yf subunit of glutathione S-transferase P shows regional variation in the staining of epithelial cells of the testis, efferent ducts, and epididymis of the male rat.

Glutathione S-transferases (GSTs) are a family of isozymes that catalyze the conjugation of glutathione (GSH), a tripeptide found in all mammalian cells; this function plays a protective role, as the addition of GSH to an electrophile generally forms a less toxic product. The pi class of GSTs contains homodimers of the Yf subunit, also known as Yp or rat subunit 7; this subunit is found in high concentrations in the testis and epididymis. The objective of the present study was to localize immunocytochemically the Yf subunit in the testis and in the various regions of the epididymis using light, electron, and confocal microscopy.

Multiple sclerosis: a comparison of the latent periods of different populations.

While some research in multiple sclerosis has concentrated on the latent period of this disease in single population groups, none has attempted to carry out significance tests to compare the distributions of the latent periods of two distinct groups. Two comparisons are made here, between the populations attending the Multiple Sclerosis Clinic of the Montreal Neurological Institute and Hôpital Neurologique et Neuro-Chirurgical Pierre-Wertheimer, Lyon. We also compared the latent period separately in males and females.