Publications by authors named "J P Van geertruyden"

Background: Although there are several areas in southern Ethiopia environmentally favourable for cutaneous leishmaniasis (CL), studies on the existence and risk factors of CL are lacking beyond a few well-known hotspots. This study aimed to assess the prevalence and risk factors of CL in Bilala Shaye, a village in the southern Ethiopian highlands at an altitude of 2,250 meters.

Methods: A cross-sectional house-to-house survey was done between July-August 2021.

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The Democratic Republic of the Congo (DRC) struggles with low full childhood vaccination coverage (around 50 %) and a high children-under-five mortality rate (79 deaths per 1000 live births). This situation is potentially exacerbated by vaccine hesitancy, which was identified by the World Health Organization (WHO) as one of the top 10 global health threats in 2019. To gain deeper insights into levels of vaccine confidence possibly influencing vaccination coverage, we explored perceptions and attitudes towards childhood and adult vaccines in Boende (Tshuapa province, western DRC), which experienced an Ebola outbreak in 2014 and hosted the EBL2007 Ebola vaccine trial (2019-2022).

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Objective: Non-communicable diseases (NCDs) increasingly contribute to maternal morbidity and mortality. We determined the association between NCDs and obstetric complications at Mbarara Regional Referral Hospital (MRRH) in southwestern Uganda.

Methods: In this retrospective records review, we randomly selected records of women admitted for delivery at MRRH each month from January to December 2022, and extracted their socio-demographic and clinical histories.

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Article Synopsis
  • * This study looked at the pharmacokinetics (how the drugs move and are processed in the body) of amodiaquine, desethylamodiaquine, and piperaquine in pregnant women during their second and third trimesters with uncomplicated malaria.
  • * Results showed that while amodiaquine's absorption increased with gestational age, the exposure to desethylamodiaquine and piperaquine in pregnant women was similar to that in non-pregnant women, indicating that dose adjustments are unnecessary for these patients.
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Article Synopsis
  • * A study conducted from November 2019 to May 2020 found persistent malaria cases, with high infection rates and limited genetic diversity among the local parasite populations.
  • * Notably, resistance to anti-malarial drugs was identified, emphasizing the need for targeted strategies to address unique mobility patterns and prevent imported malaria infections in these remote areas.
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