From Beam Damage to Massive Reaction Amplification under the Electron Microscope: An Ionization-Induced Chain Reaction in Crystals of a Dewar Benzene.

Electron microscopy in its various forms is one of the most powerful imaging and structural elucidation methods in nanotechnology where sample information is generally limited by random chemical and structural damage. Here we show how a well-selected chemical probe can be used to transform indiscriminate chemical damage into clean chemical processes that can be used to characterize some aspects of the interactions between high-energy electron beams and soft organic matter. Crystals of a Dewar benzene exposed to a 300 keV electron beam facilitate a clean valence-bond isomerization radical-cation chain reaction where the number of chemical events per incident electron is amplified by a factor of up to ca.

Polygenic score distribution differences across European ancestry populations: implications for breast cancer risk prediction.

Background: The 313-variant polygenic risk score (PRS) provides a promising tool for clinical breast cancer risk prediction. However, evaluation of the PRS across different European populations which could influence risk estimation has not been performed.

Methods: We explored the distribution of PRS across European populations using genotype data from 94,072 females without breast cancer diagnosis, of European-ancestry from 21 countries participating in the Breast Cancer Association Consortium (BCAC) and 223,316 females without breast cancer diagnosis from the UK Biobank.

Longitudinal determinants of thriving in Puerto Rican climate crisis migrants on the U.S. mainland: A structural equation model.

Climate-related disasters pose significant risks to mental health and well-being globally. Individuals from disaster-prone regions, such as Puerto Rico, are at even greater risk. The devastating effects of recurrent hurricanes, compounded with pre-existing structural disparities (e.

New Label-Free DNA Nanosensor Based on Top-Gated Metal-Ferroelectric-Metal Graphene Nanoribbon on Insulator Field-Effect Transistor: A Quantum Simulation Study.

In this paper, a new label-free DNA nanosensor based on a top-gated (TG) metal-ferroelectric-metal (MFM) graphene nanoribbon field-effect transistor (TG-MFM GNRFET) is proposed through a simulation approach. The DNA sensing principle is founded on the dielectric modulation concept. The computational method employed to evaluate the proposed nanobiosensor relies on the coupled solutions of a rigorous quantum simulation with the Landau-Khalatnikov equation, considering ballistic transport conditions.

Heterogeneous integration of GaInAsSb-GaSb photodiodes on SOI photonic integrated circuits for SWIR applications.

We demonstrate the heterogeneous integration of GaInAsSb-GaSb photodiodes on 220 nm SOI photonic integrated circuits (PICs) using the micro-transfer-printing (μTP) technology, for operation in the short-wave infrared (SWIR) wavelength region. Utilizing an evanescent coupling scheme between a silicon waveguide and a III-V structure, the device exhibits a room temperature responsivity of 1.23 and 1.