Publications by authors named "J P Rizzi"
In-hospital evolution of secondary mitral regurgitation in acutely decompensated heart failure.
J Cardiovasc Med (Hagerstown)
November 2024
Aims: Secondary mitral regurgitation (MR) negatively affects prognosis in acutely decompensated heart failure (ADHF), but can be rapidly sensitive to changes in volume status and medical interventions. We sought to assess the evolution of secondary MR in patients hospitalized for ADHF and its prognostic implications.
Methods: We retrospectively enrolled 782 patients admitted for ADHF with at least two in-hospital echocardiographic evaluations of MR.
Article Synopsis
- Secondary tricuspid regurgitation (TR) is linked to worse outcomes in patients with acute decompensated heart failure (ADHF), and this study investigates how TR changes during hospital treatment and its impact on patient prognosis.
- The research included 1054 ADHF patients, finding that nearly half (49%) of those with severe TR at admission improved during their hospital stay, which correlated with better recovery and lower long-term risk of dying or being readmitted for heart failure.
- Factors like atrial fibrillation and higher diuretic doses were associated with less likelihood of TR improvement, but better TR status was significantly tied to better 5-year survival rates and heart failure hospitalization outcomes.
The herbicide triclopyr (3,5,6-trichloro-2-pyridinyloxyacetic acid) is already considered an environmental problem due to damage caused by incorrect disposal, leaching, and aerial dispersion, which may pose risks to the environment and human health. Studies have evaluated metabolism, absorption, excretion, and active transport but there is no clear information about its mode of action (MoA) and its cytotoxic action potential remains unknown. In this context, mitochondria have been used to assess the toxicity of xenobiotics, for this reason, to identify the toxic mechanism of triclopyr, hepatic mitochondria from Wistar rats were exposed to different concentrations of triclopyr (0.
View Article and Find Full Text PDFAim: Liver damage frequently occurs in patients with cardiovascular (CV) disease and is associated with adverse clinical outcomes. The associations of liver damage with cardiac structure/function measures and the risk of adverse CV events in patients with dilated cardiomyopathy (DCM) are poorly known.
Methods: We retrospectively enrolled consecutive patients with DCM undergoing cardiac magnetic resonance imaging (MRI).
Article Synopsis
- Tricuspid regurgitation (TR) is a common issue in chronic heart failure and negatively impacts prognosis, especially in patients admitted for acute heart failure (HF); however, this study investigates the relationship between TR and mortality in acute HF cases.* -
- The research included 1,176 patients, finding that 29.9% had moderate to severe TR, which correlated with older age and more health complications; moderate-severe TR significantly increased the risk of death within one year regardless of other health factors.* -
- Specifically, those with both moderate-severe TR and pulmonary hypertension faced a threefold increase in one-year mortality risk compared to those without TR or PH, highlighting the critical impact of concurrent conditions on patient