Publications by authors named "J P Pignol"
Background And Purpose: The quality of the Cone Beam Computed Tomography (CBCT) images used for patient set-up is essential to avoid geographical miss when narrower margins or shorter fractionation are used for example in Accelerated Partial Breast Irradiation (APBI). This study evaluates deep inspiration breath hold (DIBH) with skin guided radiotherapy as a tool for image improvement reducing motion artifacts.
Materials And Methods: Daily CBCT images of left and right breast cancer patients with well-defined surgical cavity on CT simulation were used for this study.
Comparison of stereotactic radiotherapy and protons for uveal melanoma patients.
Phys Imaging Radiat Oncol
July 2024
Article Synopsis
- * The study analyzed data from 66 UM patients, assessing 14 different dose-volume parameters and evaluating four toxicity profiles, including visual impairment and radiation-induced conditions.
- * Results indicated that proton therapy often had advantages in reducing toxicity risks compared to SRT, particularly for higher-stage tumors, although the choice of treatment may depend on individual risk priorities.
Article Synopsis
- Accurate determination and verification of monitor units are vital for effective dose distribution in radiotherapy, particularly in ocular proton therapy for eye melanoma.
- A multi-institutional study involving three European institutes aimed to create a generalized model for predicting monitor units using data from 3,748 patients and various machine learning algorithms.
- The model showed promising results, achieving predictions within 3% uncertainty for 85.2% of plans and within 10% for 98.6% of plans, signifying a potential advancement in treatment planning systems.
Objective: To investigate the potential of hybrid Pd/Fe-oxide magnetic nanoparticles designed for thermo-brachytherapy of breast cancer, considering their specific loss power () and clinical constraints in the applied magnetic field.
Methods: Hybrid nanoparticles consisting of palladium-core and iron oxide shell of increasing thickness, were suspended in water and their were measured at varying magnetic fields (12-26 mT peak) and frequencies (50-730 kHz) with a commercial alternating magnetic field generator (magneTherm™ Digital, nanoTherics Ltd.).