Anatomically corrected malposition (ACM) of the great arteries is an exceedingly rare congenital heart disease. This conotruncal anomaly manifests with an L-malposition of the aorta (situs solitus, D loop, aorta to the left of the pulmonary artery) with normal ventriculoarterial concordance. A 14-month-old boy presented with an ACM associated with a ventricular septal defect that was successfully repaired.
View Article and Find Full Text PDFThe source of nitrous acid (HONO) and its importance in island or marine environments are poorly understood. Herein, based on comprehensive field measurements at a hilltop on Corsica Island, we find an inverse diel variation of HONO with higher concentrations during daytime. Night-time HONO budget analysis indicates significant HONO formation during air mass transport along the hillside.
View Article and Find Full Text PDFCarbonaceous aerosols (CA), composed of black carbon (BC) and organic matter (OM), significantly impact the climate. Light absorption properties of CA, particularly of BC and brown carbon (BrC), are crucial due to their contribution to global and regional warming. We present the absorption properties of BC (b) and BrC (b) inferred using Aethalometer data from 44 European sites covering different environments (traffic (TR), urban (UB), suburban (SUB), regional background (RB) and mountain (M)).
View Article and Find Full Text PDFAm J Med Genet B Neuropsychiatr Genet
December 2024
Anorexia nervosa (AN) is a psychiatric disorder with an estimated heritability of around 70%. Although the largest meta-analysis of genome-wide association studies on AN identified independent risk-conferring loci for the disorder, the molecular mechanisms underlying the genetic basis of AN remain to be elucidated. To investigate AN, we performed transcriptome profiling in peripheral blood mononuclear cells from 15 AN patients and 15 healthy controls.
View Article and Find Full Text PDF