Publications by authors named "J P Nicol"

Although Hepatitis C virus (HCV) infection can be cured with direct-acting antivirals (DAA), some cured patients face a serious risk of advanced liver damage and early mortality. In order to avoid these two negative health outcomes, it is important to identify and assess related risk factors. Little is currently known about socioeconomic and behavioural factors in this context.

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  • Australian wheat breeders access wheat germplasm through the CAIGE program, which coordinates the selection, import, quarantine, and evaluation of this germplasm for the Australian wheat industry.
  • The CAIGE model has been validated through trials from 2017 to 2020, showing significant yield improvements from germplasm contributions compared to non-CAIGE varieties.
  • Investing in CAIGE has proven highly profitable, offering a benefit-cost ratio of $20 for every dollar spent, indicating substantial economic returns and ongoing benefits for Australian wheat breeding.
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Purpose: Supporting the relational worlds of people living with dementia, especially the spousal dyad, is a growing focus in dementia care as is advancing the therapeutic use of music in dementia care. This paper describes a mixed-methods, multi-phase, iterative research study designed to develop the Music Memory Makers (MMM) Duet System, a novel therapeutic music technology, that allows non-musicians to play a personalized repertoire of songs arranged as duets.

Methods: Following a pilot phase to iteratively assess and refine the MMM Duet System for recreational and therapeutic purposes, multiple sources of data were used to investigate five older spousal dyads' experiences with the system, two couples living with dementia and three who were not.

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Background: Undergraduate nursing programme teaching and learning methods and content must evolve to meet the changing evidence base, healthcare context and needs of new generations of nurses. Art-based and narrative methods have been employed to help student nurses explore complex issues, including patient experiences of health and illness, person-centred care and social determinants of health. One creative visual teaching tool is the graphic novel.

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  • The prediction of RNA structure from its sequence is challenging due to a lack of experimental data, which has slowed advancement in the field.
  • Researchers have developed a dataset called Ribonanza, consisting of chemical mapping data from two million RNA sequences, collected through crowdsourcing platforms like Eterna.
  • Utilizing this dataset, they created a deep learning model named RibonanzaNet, which, when fine-tuned, demonstrates superior performance in predicting various RNA behaviors, potentially improving understanding of RNA structures.
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