Effect of 5-fluorouracil and mitomycin on the healing of intestinal anastomosis.

Objective: Antineoplastic agents affect the healing of intestinal anastomosis. The aim was to evaluate the effect of 5-fluorouracil (5-FU) and mitomycin on the healing of the intestinal anastomosis and their schedule of administration.

Material And Methods: Eighty-nine male albino Charles Foster rats with a mean weight of 256.

Pharmacological evaluation of some bioactive plant products on albino rats.

The study comprises the pharmacological trials with essential oils of Caesulia axillaris, Ocimum gratissimum and Mentha arvensis which have shown strong antifungal property. The biochemical analysis of blood and serum of albino rats fed with the oil treated diet for sixty days exhibited nonanimal toxic nature of the oils. The study reveals the possibility of further exploitation of the oils as safe antifungal agents of plant origin.

Hypolipidemic activity of aqueous extract of Withania coagulans Dunal in albino rats.

Administration of an aqueous extract of fruits of Withania coagulans (1 g/kg; p.o.) to high fat diet induced hyperlipidemic rats for 7 weeks, significantly reduced elevated serum cholesterol, triglycerides and lipoprotein levels.

Hypoglycemic activity of Withania coagulans Dunal in streptozotocin induced diabetic rats.

Administration of aqueous extract of fruits of Withania coagulans Dunal significantly lowered the blood sugar, serum cholesterol, serum LPO, and hepatic LPO levels at the highest concentration of 1g/kg; p.o. in streptozotocin induced diabetic rats.

Healing process in the ureter: an experimental study in dogs.

Objective: This study set out to describe the basic milestones in the pattern of healing in the ureter in order to understand why problems in healing arise when the ureter is severed, usually through anastomotic leakage or stricture formation.

Method: Transection and anastomosis of the ureter were performed on dogs. The anastomotic segment was removed at days 6, 14, 21 and 42.