Insulin resistance in patients with cancer: a systematic review and meta-analysis.

Background: Insulin resistance is a critical cause of metabolic dysfunctions. Metabolic dysfunction is common in patients with cancer and is associated with higher cancer recurrence rates and reduced overall survival. Yet, insulin resistance is rarely considered in the clinic and thus it is uncertain how frequently this condition occurs in patients with cancer.

Why are some people more attractive to mosquitoes than others?

Mosquitoes rely on their sense of smell to find humans to secure a blood meal, transmitting deadly diseases with their bite. In this issue of Cell, De Obaldía and colleagues examine why mosquitoes bite some people more than others and report an association with the level of carboxylic acids in the human skin odor.

The structural basis of odorant recognition in insect olfactory receptors.

Olfactory systems must detect and discriminate amongst an enormous variety of odorants. To contend with this challenge, diverse species have converged on a common strategy in which odorant identity is encoded through the combinatorial activation of large families of olfactory receptors, thus allowing a finite number of receptors to detect a vast chemical world. Here we offer structural and mechanistic insight into how an individual olfactory receptor can flexibly recognize diverse odorants.

Author Correction: Microbiota modulate sympathetic neurons via a gut-brain circuit.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.