Publications by authors named "J P Madura"
Article Synopsis
- Extrusion welding of AlMgSi(Cu) alloys using porthole dies creates hollow shapes with seam welds, but improper alloy composition or conditions can weaken the weld's strength compared to the base material.
- Predictive modeling of welding conditions based on alloy composition, temperature, and pressures streamlines porthole die design, reducing necessary testing and production costs.
- Laboratory tests on two AlMgSi(Cu) alloy compositions showed that optimal welding at 550°C and 350 MPa resulted in significant weld strength, with the highest relative weld strength recorded at 87% for one alloy.
Article Synopsis
- Obese patients have higher complication rates after breast reconstruction, and this study investigates how bariatric surgery can reduce those risks.
- An analysis of 1,026 patients over five years showed a significant decrease in surgical complications after bariatric surgery, with a reduction in risk from 40.4% to 24.8%.
- Results suggest that even small decreases in BMI before surgery can lead to substantial reductions in complications, highlighting the potential benefits of weight loss interventions for patients seeking breast reconstruction.
In the realm of modern architecture, the demand for materials that combine strength, durability, and aesthetic flexibility is ever-growing. Addressing this need, this paper presents a study on the innovative use of aluminum extrudates in construction. Focusing on the AA6005 alloy, which is known for its excellent balance of strength, corrosion resistance, and weldability, this research delves into the development of an extrusion process that yields thin-walled, lightweight, yet high-strength structural components.
View Article and Find Full Text PDFImportance: Cancer is one of the leading causes of death in the United States, with the obesity epidemic contributing to its steady increase every year. Recent cohort studies find an association between bariatric surgery and reduced longitudinal cancer risk, but with heterogeneous findings.
Observations: This review summarizes how obesity leads to an increased risk of developing cancer and synthesizes current evidence behind the potential for bariatric surgery to reduce longitudinal cancer risk.
Article Synopsis
- Obesity is linked to insulin resistance (IR) and high leptin levels, with recent mouse studies indicating that lowering leptin can improve IR.
- Eosinophils in adipose tissue produce IL-4, which helps regulate leptin; however, their levels are reduced in diet-induced obesity, raising questions about their role in humans.
- A study found that obese individuals had lower eosinophil content and IL-4 levels, alongside increased leptin and IR, suggesting potential avenues for treatment by targeting this eosinophil-IL-4-leptin relationship.