Publications by authors named "J P Lynch"

Background: Despite the widespread adoption of selective antegrade cerebral perfusion (SACP) for neonatal aortic arch reconstruction, significant variability in techniques persists across institutions, reflecting limited supporting data and lack of consensus on best practices. This review aims to comprehensively characterize the utilization of SACP in the extant literature and highlight variation in practice to guide future research and standardization of care.

Methods: A comprehensive search was conducted using Embase, Medline/OVID, and NCBI/PubMed databases to identify studies published from 1999-2024 that contained the following terms: ('neonatal' OR 'neonate' OR 'newborn') AND ('aortic arch' OR 'Norwood' OR 'stage one') AND ('circulatory arrest' OR 'cerebral perfusion').

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Specialized, maternally derived ribonucleoprotein (RNP) granules play an important role in specifying the primordial germ cells in many animal species. Typically, these germ granules are small (∼100 nm to a few microns in diameter) and numerous; in contrast, a single, extremely large granule called the oosome plays the role of germline determinant in the wasp The organizational basis underlying the form and function of this unusually large membraneless RNP granule remains an open question. Here we use a combination of super-resolution and transmission electron microscopy to investigate the composition and morphology of the oosome.

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Phylogenetic trees are analytic tools used in primate studies to elucidate evolutionary relationships. Because of its relative ease to sequence and rapid evolution compared to nuclear genomes, mitochondrial DNA is frequently used for phylogeny building. This project evaluated the effectiveness of using individual or grouped mitochondrial genes (mtGenes) as a proxy for the mitochondrial genome (mtGenome) in phylogeny building within two nested primate datasets, Cebidae and Platyrrhini, with differing divergence dates.

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Atmospheric deposition of nitrogen and sulfur, after land use change, is one of the most impactful stressors to terrestrial biodiversity. Deposition effects on ecosystems are pervasive, impacting species distributions and disrupting natural communities and associated ecosystem services. Decision makers in particular areas have in the past been limited to using critical loads from faraway research sites or from networks of plots that may or may not overlap with or represent their particular management area.

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