Publications by authors named "J P Leventhal"

While rare, life-threatening dermatoses encompass various inflammatory, infectious, vasculitic/vasculopathy, paraneoplastic, and neoplastic skin diseases. Complications include skin barrier dysfunction, secondary infection, and internal organ involvement. Skin signs may serve as a critical window into systemic disease.

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Introduction: Targeted therapy has improved clinical outcomes for various types of cancer. However, their use is associated with dermatologic adverse events that impact quality of life and consistent therapies.

Objectives: The US Cutaneous Oncodermatology Management (USCOM) multidisciplinary-guided algorithm for preventing and managing cutaneous targeted therapy-related adverse events provides practical recommendations for cancer patients and survivors.

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Article Synopsis
  • VEXAS syndrome is characterized by an abnormal immune response involving neutrophils but recent studies show that other cell types can also be present in the infiltrates.
  • The report discusses three cases of VEXAS syndrome, highlighting a total of seven biopsies, which revealed a consistent presence of histiocytoid cells with a distinctive feathery cytoplasm.
  • These histiocytoid cells may serve as an important diagnostic indicator for identifying VEXAS syndrome.
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Objectives: There is little understanding of the circumstances behind fatal pediatric opioid poisonings. Our objective was to characterize opioid fatalities according to child, family, and household factors.

Methods: We used data from the National Fatality Review-Case Reporting System to describe the circumstances behind the deaths of children 0 to 17 years of age who died of an opioid poisoning (ie, prescription opioid, heroin, illicit fentanyl) between 2004 and 2020.

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