Publications by authors named "J P Lejeune"

Background Delivering care that is responsive to who or what is most important to patients and family caregivers is a key aspect of quality care, yet it remains unclear how clinicians can best support individuals in expressing their personal values. We aimed to describe patient- and family caregiver-identified facilitators and barriers to engaging in values discussions with clinicians following implantation of a left ventricular assist device (LVAD). Methods and results Using a qualitative descriptive approach, patients with an LVAD and their caregivers participated in one-on-one semi structured interviews and self-reported sociodemographics (January 2023-July 2023).

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  • The study investigates the relationship between socioeconomic status (SES) and time to diagnosis (TTD) in childhood cancer, noting that a clearer connection has been observed in adults.
  • A retrospective analysis involving 854 children revealed a median TTD of 28 days, with variations based on tumor type but no significant link between SES factors and TTD.
  • Initial treatment by non-specialized professionals was associated with longer TTD, while overall, TTD did not appear to influence children's survival or relapse rates, indicating a need for further research on individual SES impacts.
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  • Hematological involvement (HI) is a serious condition associated with Langerhans cell histiocytosis (LCH), and is defined by low blood cell counts indicating potential life-threatening complications.
  • A study of 2,313 children with LCH revealed that about 331 developed HI, with a distinction between mild (MHI) and severe HI (SHI), each showing different health outcomes and survival rates over 10 years.
  • Recent advances in treatment have improved mortality rates, particularly with combination therapies and targeted treatments, sparking discussions about refining HI definitions to better inform treatment strategies.
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  • * The study examined 266 young horses in Wallonia for correlations between conformation traits (foot and fetlock angles and height at withers) and the presence of these fragments, utilizing radiographic screenings.
  • * Key findings showed significant links between specific foot angles and fragment presence, including a notable palmar angle correlation, while an optimal cut-off for predicting fragment presence based on height at withers and bone diameter was established.
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Osteochondrosis dissecans is a particularly common developmental orthopaedic disorder in equines. Among its causes, the hereditary component is no longer a matter of debate, and, for several decades, the various studbooks for sport horses have been selecting stallions in order to limit the prevalence of this condition in the population. However, to our knowledge, no study has evaluated changes in the prevalence of osteochondrosis dissecans over time through longitudinal monitoring of a population of sport horses.

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