Publications by authors named "J P Lefaucheur"
Multiple sclerosis (MS) is a central nervous system disease involving gray and white matters. Transcranial magnetic stimulation (TMS) and magnetic resonance imaging (MRI) could help identify potential markers of disease evolution, disability, and treatment response. This work evaluates the relationship between intracortical inhibition and facilitation, motor cortex lesions, and corticospinal tract (CST) integrity.
View Article and Find Full Text PDFHere, we present five different insights on the use of neuromodulation strategies for effective pain management in clinical practice. Experts briefly illustrate the various techniques available and the complexities involved in evaluating their effectiveness. Additionally, they highlight the challenges for widespread adoption in clinical practice and explore some future directions.
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- A trial was conducted to assess the effects of the EXOPULSE Mollii Suit, a device that provides electrical nerve stimulation, on fibromyalgia symptoms including pain, fatigue, and quality of life.
- The study involved 33 adult patients with fibromyalgia in a double-blind, sham-controlled trial, demonstrating significantly reduced pain and improved symptoms after using the active device compared to the sham treatment.
- Results showed that after a 4-week active treatment period, most patients reported improvements in various outcomes, highlighting the potential clinical benefits of the EXOPULSE Mollii Suit for managing fibromyalgia symptoms.
Background: Repetitive transcranial magnetic stimulation (rTMS) of the primary motor cortex (M1) at high frequency (HF) is an effective treatment of neuropathic pain. The classical HF-rTMS protocol (CHF-rTMS) includes a daily session for one week as an induction phase of treatment followed by more spaced sessions. Another type of protocol without an induction phase and based solely on spaced sessions of HF-rTMS (SHF-rTMS) has also been shown to produce neuropathic pain relief.
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- - Fabry disease (FD) is a rare genetic disorder linked to the GLA gene and is marked by a range of symptoms affecting various organs, often signaled by chronic pain.
- - Two studies were conducted to determine the prevalence of FD in chronic pain patients, testing alpha-galactosidase A activity in men and analyzing the GLA gene in women.
- - The findings indicated that FD's prevalence in this group is about 1 in 1000 individuals, suggesting that while routine screening for FD in chronic pain patients is not essential, awareness of its symptoms is crucial for diagnosis, especially with family histories of the disease.