Publications by authors named "J P Lazareth"

Article Synopsis
  • The study investigates the effectiveness of whole-body muscle MRI (WB-mMRI) in identifying underlying myopathy in patients with bent spine syndrome (BSS) that is not associated with extrapyramidal conditions.
  • Forty-three patients, primarily women aged between 53-86, underwent WB-mMRI and nerve conduction studies; muscle biopsies were conducted if necessary based on the results.
  • The study found that WB-mMRI successfully identified all myopathies in five cases and highlighted its role in directing when a muscle biopsy is needed, while emphasizing the importance of careful MRI interpretation for incidental findings.
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Intracranial lipomas are rare lesions the pathogenesis of which is still a matter of debate. We report the case of a patient presenting an asymptomatic lipoma located in the quadrigeminal and supra-cerebellar cisterns. The lipoma was associated with hypoplasia of the right inferior colliculus and of the rostral part of the vermis.

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A 38 year old patient developed multiple cranial nerve palsy, seizures and progressive alteration in consciousness. CSF examination revealed tumor cells and a tentative diagnosis of leptomeningeal carcinomatosis from an unknown primary tumor was made. Treatment with intrathecal methotrexate and cranial radiation therapy was started without effect.

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