Background: The essential amino acid leucine (LEU) plays a crucial role in promoting resistance-training adaptations. Dileucine (DILEU), a LEU-LEU dipeptide, increases MPS rates, however its impact on resistance training outcomes remains unexplored. This study assessed the effects of DILEU supplementation on resistance training adaptations.
View Article and Find Full Text PDFUnlabelled: Flavonoids, known for their neuroprotective properties, are abundant in and Yet, human studies on their combined effects are limited.
Objective: This study evaluated the cognitive effects of combined and supplementation in healthy adults.
Methods: In a randomized, double-blind, placebo-controlled trial, 26 males and 59 females ( = 85; 43 ± 8 yrs) consumed the test product (TP) containing 240 mg stem extract of and 51 mg heartwood extract of (UP326, Unigen, Tacoma, WA USA) or placebo (PLA) for four weeks.
The emerging field of orbitronics aims to generate and control orbital angular momentum for information processing. Chiral crystals are promising orbitronic materials because they have been predicted to host monopole-like orbital textures, where the orbital angular momentum aligns isotropically with the electron's crystal momentum. However, such monopoles have not yet been directly observed in chiral crystals.
View Article and Find Full Text PDFPurpose: Vascular endothelial growth factor (VEGF) inhibition is the current and high-volume standard-of-care for patients with neovascular age-related macular degeneration (nAMD) and diabetic retinopathy (DR) with diabetic macular edema (DME). This study assessed the impact of non-persistence in anti-VEGF treatment using claims data from two German states.
Methods: This study identified adults with nAMD or DR/DME and incident anti-VEGF treatment (= index) in January 2015-June 2019 using the German AOK PLUS claims database (January 2014-June 2021, ~ 3.