Direct View of Gate-Tunable Miniband Dispersion in Graphene Superlattices Near the Magic Twist Angle.

Superlattices from twisted graphene mono- and bilayer systems give rise to on-demand many-body states such as Mott insulators and unconventional superconductors. These phenomena are ascribed to a combination of flat bands and strong Coulomb interactions. However, a comprehensive understanding is lacking because the low-energy band structure strongly changes when an electric field is applied to vary the electron filling.

Evaluation of RMplex system for differentiating father-son pairs using Y-STRs in a Korean population.

Y-chromosomal short tandem repeats (Y-STRs) at rapidly mutating (RM) loci have been suggested as tools for differentiating paternally related males. RMplex is a recently developed system that incorporates 26 RM loci and four fast-mutating (FM) loci, targeting 44 male-specific loci. Here, we evaluated the RMplex by estimating Y-STR mutation rates and the overall differentiation rates for 542 Korean father-son pairs, as well as the genetic population values for 409 unrelated males.

Biomarkers.

Background: Alzheimer's disease (AD) pathology occurs in the brain before manifestation of significant cognitive decline. Growing evidence suggests that brain networks such as default mode network (DMN) or salience network, identified through resting-state functional magnetic resonance imaging (MRI), are affected by AD pathology. In this study, we investigated the relationship between network segregation and the key in vivo AD pathologies including beta-amyloid (Aβ) and tau deposition in old adults with no cognitive impairment.

Biomarkers.

Background: Rapid eye movement(REM) sleep alterations are increasingly recognized as an early manifestation of Alzheimer's disease as well as Lewy body disease. The pedunculopontine nucleus(PPN), the main brain source of cholinergic innervation, is known to play an important role in the regulation of REM sleep and has been reported to be one of the early brainstem regions where hyperphosphorylated tau accumulates. Nevertheless, little information is available about the relationship between tau pathology in the PPN(PPN-tau) and REM sleep disturbance.

Biomarkers.

Background: Semantic cognition refers to our ability to manipulate and generalize knowledge and plays a critical role in communication and daily activities. Therefore, impairments in semantic cognition can have a severe impact on quality of life (e.g.