Substance use during pregnancy and personality dimensions.

Our aim was to assess personality traits associated with substance use during pregnancy in a population-based, multicentre study of 1804 pregnant women. On day 2-3 postpartum, participants completed a semi-structured interview, including self-reported drug use (alcohol, tobacco, caffeine, cannabis, cocaine, opioids) during pregnancy, and socio-demographic, reproductive and obstetric variables, personal and family psychiatric history, social support, and the Eysenck personality questionnaire, short version (EPQ-RS). Logistic regression models were conducted.

The Challenges of Monoaxial Bone Transport in Orthopedics and Traumatology.

Background: Bone defects represent the main challenging problem for the orthopedic surgeon and, consequently, they increase the duration of hospitalization, risk of complications and health expenditures. The aim of our observational, descriptive and retrospective study is to evaluate the outcomes of patients treated with a mo-nolateral external fixator for bone defects greater than 3 cm.

Material And Methods: Between January 2003 and January 2013, 21 patients were treated at our center by bone transfer with a monolateral external fixator.

Relative Termination via Dependency Pairs.

A term rewrite system is terminating when no infinite reduction sequences are possible. Relative termination generalizes termination by permitting infinite reductions as long as some distinguished rules are not applied infinitely many times. Relative termination is thus a fundamental notion that has been used in a number of different contexts, like analyzing the confluence of rewrite systems or the termination of narrowing.

Regulation of bacterial physiology by lysine acetylation of proteins.

Post-translational modification of proteins is a reversible mechanism of cellular adaptation to changing environmental conditions. In eukaryotes, the physiological relevance of N-ɛ-lysine protein acetylation is well demonstrated. In recent times, important roles in the regulation of metabolic processes in bacteria are being uncovered, adding complexity to cellular regulatory networks.

Metabolic engineering for high yielding L(-)-carnitine production in Escherichia coli.

Background: L(-)-carnitine production has been widely studied because of its beneficial properties on various diseases and dysfunctions. Enterobacteria possess a specific biotransformation pathway which can be used for the enantioselective production of L(-)-carnitine. Although bioprocesses catalyzed by enzymes or whole cells can overcome the lack of enantioselectivity of chemical methods, current processes for L(-)-carnitine production still have severe disadvantages, such as the low yields, side reactions and the need of high catalyst concentrations and anaerobic conditions for proper expression of the biotransformation pathway.