Publications by authors named "J P Herve"

Key Points: A negative change in serum sodium during a dialysis session is an independent factor associated with prolonged dialysis recovery time. Lower hemoglobin is an independent factor associated with fatigue in hemodialysis patients. Hemodiafiltration use in patients age ≥85 years is associated with a longer dialysis recovery time.

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Article Synopsis
  • - Diabetes is a significant public health issue influenced by genetic and environmental factors, with some models, like monogenic forms in mice, helping to understand the disease better.
  • - A study involving NOD mice with a specific genetic mutation (Akt2 invalidation) showed that these mice developed severe hyperglycemia early on, particularly in males, without the influence of an autoimmune response.
  • - The research found that the HYP mice exhibited hyperinsulinemia before hyperglycemia and had lower insulin levels in their pancreas compared to NOD mice, suggesting that failure of beta cells is a key factor in the development of diabetes.
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Hair cortisol is a stress indicator and could be used to assess the pigs' exposure to stressors in the weeks/months prior to non-invasive hair sampling. The main aim of this study was to describe the hair cortisol concentration (HCC) variability between individuals within a batch, between farms and between batches within a farm. The secondary aim was to determine how the number of sampled pigs influences the characterization of HCC within a batch.

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Background: Around 25% of patients who have had a stroke suffer from severe upper-limb impairment and lack effective rehabilitation strategies. The AVANCER proof-of-concept clinical trial (NCT04448483) tackles this issue through an intensive and personalized-dosage cumulative intervention that combines multiple non-invasive neurotechnologies.

Methods: The therapy consists of two sequential interventions, lasting until the patient shows no further motor improvement, for a minimum of 11 sessions each.

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Nowadays, most pigs are raised indoors, on intensive farms providing a poor environment. In these conditions, the risk of the occurrence of damaging behaviours is high, with dramatic consequences for animal health and welfare as well as economic losses for farmers. Early-life conditions may predispose individuals to develop damaging behaviours later in life.

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