Publications by authors named "J P Hedrick"
Article Synopsis
- * Current research seeks to understand T1D and develop new treatments, including immune system modulation, β-cell regeneration, and advanced insulin delivery methods like closed-loop pumps and stem cell therapies.
- * Recent studies suggest that TNF-α inhibitors could help preserve β-cell function in people with advanced T1D, prompting experts to convene and plan pivotal clinical trials to further evaluate their effectiveness.
Article Synopsis
- - Organocatalyzed ring-opening polymerization (ROP) is a method for creating biodegradable polymers like polyesters and polycarbonates, and the new OPBU (di)anions are introduced as efficient catalysts that improve selectivity and speed.
- - OPBU catalysts can achieve high conversion rates of over 95% in a very short time, producing polymers with precise molecular weights and minimal dispersities, indicating nearly ideal polymerization.
- - The research shows that OPBU catalysts stabilize the transition state in the polymerization process through a hydrogen bond pocket, similar to natural enzymatic catalysis, making them a promising option for controlled polymer synthesis.
Carbon dioxide (CO) is an abundant C1 feedstock with tremendous potential to produce versatile building blocks in synthetic applications. Given the adverse impact of CO on the atmosphere, it is of paramount importance to devise strategies for upcycling it into useful materials, such as polymers and fine chemicals. To activate such stable molecule, superbases offer viable modes of binding to CO.
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