[Carcinoma of the colon in Iceland 1955-1989. A study on pathology.].

Objective: The objective of this study was to investigate various pathological parameters of colon carcinoma in Iceland in the 35 year time period from 1955-1989, and changes in these parameters during the study period.

Material And Methods: Information on all patients diagnosed with colon carcinoma in the study period was obtained from the Icelandic Cancer Registry. All pathology reports and autopsy reports were checked.

[Carcinoma of the colon in Iceland 1955-1989. An investigation of survival according to various pathological parameters.].

Objective: The purpose of this study was to estimate various pathological parameters of colon carcinoma over a 35 year time period and evaluate their effect on survival of the patients.

Material And Methods: All pathological specimens from patients diagnosed with colon carcinoma in Iceland in the period 1955 to 1989 were re-evaluated in order to determine the following pathological parameters: Tumour size, gross appearance, tissue type, grade, Dukes stage, lymphatic and/or blood vessel invasion, lateral margin involvement, Jass-group of tumour, peritumoural lymphocytic infiltrate, limitation of tumour growth to bowel wall, lymph node metastases, invasive tumour margin and colloid component in adenocarcinoma. Also the following parameters were determined in every case: Age at diagnosis, sex, year of diagnosis and tumour location within the bowel.

Antitumour activity of Angelica archangelica leaf extract.

Background: The purpose of this study was to examine the effect of a leaf extract from A. archangelica on the growth of Crl mouse breast cancer cells in vitro and in vivo.

Materials And Methods: The antiproliferative activity of the extract was measured by 3H-thymidine uptake in the Crl cells in vitro.

Familial risk of lung carcinoma in the Icelandic population.

Context: The dominant role of tobacco smoke as a causative factor in lung carcinoma is well established; however, an inherited predisposition may also be an important factor in the susceptibility to lung carcinoma.

Objective: To investigate the contribution of genetic factors to the risk of developing lung carcinoma in the Icelandic population.

Design, Setting, And Participants: Risk ratios (RRs) of lung carcinoma for first-, second-, and third-degree relatives of patients with lung carcinoma were estimated by linking records from the Icelandic Cancer Registry (ICR) of all 2756 patients diagnosed with lung carcinoma within the Icelandic population from January 1, 1955, to February 28, 2002, with an extensive genealogical database containing all living Icelanders and most of their ancestors since the settlement of Iceland.

Low back pain, smoking and employment during pregnancy and after delivery - a 3-month follow-up study.

Low back pain (LBP.), smoking and employment was studied among 111 consecutive women admitted to a maternity ward over a 6-week period, 40 were primiparas and 71 multiparas. LBP was defined as any pain in the low back, irrespective of the specific cause of the pain.