Publications by authors named "J P Gregersen"
Article Synopsis
- This study examined cardiovascular screening in patients with ANCA-associated vasculitis (AAV) and found higher rates of ECG abnormalities compared to matched controls.
- A total of 1431 AAV patients were analyzed, revealing a significant link between major ECG abnormalities and increased cardiovascular mortality risk.
- The findings suggest incorporating ECG assessments into regular care for AAV patients to better manage their cardiovascular health.
Background: This study validates the application of Systematized Nomenclature of Medicine second edition (SNOMED II) codes used to describe medical kidney biopsies in Denmark in encoded form, aiming to support robust epidemiological research on the causes, treatments and prognosis of kidney diseases.
Methods: Kidney biopsy reports from 1 January 1998 to 31 December 2018 were randomly extracted from the Danish National Patobank, using SNOMED codes. A 5% sample was selected, and nephrologists assessed the corresponding medical records, assigning each case the applied clinical diagnoses.
Background: Epidemiologic assessments of anti-glomerular basement membrane (GBM) disease have been challenging due to its rare occurrence. We examined changes in the incidence and outcomes from 1998 to 2018 using nationwide healthcare registries.
Methods: All patients with incident anti-GBM disease were identified using the International Classification of Diseases, 10th Revision code DM31.
Article Synopsis
- A study was conducted to determine if patients with ANCA-associated vasculitis (AAV) are at a higher risk for cardiovascular disease before being diagnosed with AAV.
- Researchers used data from Danish registries, matching 2371 AAV patients with 7113 controls, and analyzed various cardiovascular outcomes over different timeframes leading up to the diagnosis.
- The findings revealed that AAV patients experienced significantly higher rates of cardiovascular issues, especially within a month prior to diagnosis, highlighting the need for clinicians to monitor cardiovascular health early in these patients.
Objective: To examine changes in biomarkers of endothelial glycocalyx shedding, endothelial damage, and surgical stress following major open abdominal surgery and the correlation to postoperative morbidity.
Introduction: Major abdominal surgery is associated with high levels of postoperative morbidity. Two possible reasons are the surgical stress response and the impairment of the glycocalyx and endothelial cells.