Publications by authors named "J P Govaerts"
Cold-induced vasodilation (CIVD) is a physiological response characterized by cyclic vasodilation occurring within 5-10 min of cold exposure, predominantly in the fingers and toes. This study aimed to determine the roles of body dimensions, specifically surface-to-mass (SM) ratio and sex in modulating CIVD responses. Thirty-nine participants (mean ± SD age: 24 ± 3 yr; height: 174 ± 28 cm; weight: 75.
View Article and Find Full Text PDFAggregative multicellularity is a cooperative strategy employed by some microorganisms. Unlike clonal expansion within protected environments during multicellular eukaryotic development, an aggregation strategy introduces the potential for genetic conflicts and exploitation by cheaters, threatening the stability of the social system. , a soil-dwelling bacterium, employs aggregative multicellularity to form multicellular fruiting bodies that produce spores in response to starvation.
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- Clozapine is an antipsychotic for schizophrenia that has serious side effects, making drug-drug interaction (DDI) databases important for clinician reference.
- This study analyzed DDI information from five different databases to assess their agreement on potential interactions with clozapine.
- Out of 183 potential DDIs identified, only 47.5% showed consensus across the databases, highlighting significant discrepancies that could affect patient safety and prescribing practices.
Article Synopsis
- * The findings indicate that bone needles, found at the La Prele site dating back to around 12,900 years ago, were made from the bones of canids, felids, and hares, which were chosen based on their size and availability.
- * This evidence suggests that Early Paleoindian foragers actively accessed fur-bearing predators, likely through trapping, providing insights into the complexity of their garments and their adaptation to new environments.
Dendritic cells (DCs) are critical players at the intersection of innate and adaptive immunity, making them ideal candidates for anticancer vaccine development. DC-based immunotherapies typically involve isolating patient-derived DCs, pulsing them with tumor-associated antigens (TAAs) or tumor-specific antigens (TSAs), and utilizing maturation cocktails to ensure their effective activation. These matured DCs are then reinfused to elicit tumor-specific T-cell responses.
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