Publications by authors named "J P Gardin"
National security concerns regarding radiological incidents, accidental or intentional in nature, have increased substantially over the past few years. A primary area of intense planning is the assessment of exposed individuals and timely medical management. However, exposed individuals who receive survivable radiation doses may develop delayed effects of acute radiation exposure many months or years later.
View Article and Find Full Text PDFAims: To determine whether discrete lipid profiles (refer to as lipid phenotyping) can be used to stratify cardiovascular risk in individuals with type 2 diabetes.
Methods And Results: Cardiovascular Health Study participants with diabetes and fasting lipid profiles at baseline ( = 866) were categorized separately by level of LDL cholesterol and HDL-C/Triglyceride (Tg) profiles (low Tg/high HDL-C; high Tg/low HDL-C; high Tg only or low HDL-C only). We performed Cox multivariate regression analysis to assess the risk of CVD mortality, incident myocardial infarction (MI), heart failure (HF), stroke, and composite MACE (MI, HF, stroke, and CVD mortality) associated with each lipid category.
Background: African green monkeys (AGMs, also known as vervets, Cholorocebus aethiops sabaeus) have been used in a variety of biomedical research studies. The aim of this study was to generate a reference for normal organ weights and percentage organ weights in AGMs of different age categories and sex.
Methods: The organ weights were compiled from 479 AGMs (285 females, 194 males) from 2004 to 2021.
Article Synopsis
- - Stereotactic Body Radiation Therapy (SBRT) for lung tumors can lead to chest wall pain (CWP), which affects patients’ quality of life, but the reasons behind this pain are not fully understood.
- - The study explored how radiation affects osteoclasts (bone cells) and sensory neurons, showing that radiation increases osteoclast activity and pain-associated neuropeptides in neurons.
- - The findings suggest that using inhibitors like osteoprotegerin and risedronate may help manage the pain caused by high doses of radiation in patients undergoing SBRT.
Article Synopsis
- * A study assessing data from the National Inpatient Sample found that only 2.3% of PPCM patients developed PE, but those with PE had significantly longer hospital stays and higher medical costs.
- * Key predictors of higher mortality for PPCM patients included conditions like cardiogenic shock, PE, and non-ST-elevation myocardial infarction, highlighting the need for careful monitoring and management of these patients.