Aging affects the mechanical interaction between microplastics and lipid bilayers.

Plastic pellets, the pre-production form of many plastic products, undergo oxidation and photodegradation upon exposure to oxygen and sunlight, resulting in visible color changes. This study examines the impact of environmental aging on the mechanical interactions between pellet-derived microplastics and lipid bilayers, a critical component of biological membranes. Polyethylene pellets were collected from La Pineda beach near Tarragona, Spain, and categorized by chemical composition and yellowing index, an indicator of aging.

Early Versus Late Administration of Long-Acting Insulin in Adult Diabetic Ketoacidosis.

Background: Evidence is inconclusive if early administration of subcutaneous (SQ) long-acting insulin (LAI) in management of diabetic ketoacidosis (DKA) improves outcomes.

Objective: This study compares early versus late administration of SQ LAI in time to DKA resolution.

Methods: This single-center, retrospective study included patients with DKA who received ≥12 hours of continuous intravenous insulin (CIVI) with LAI overlap.

Synergistic Effects of Microplastics and Marine Pollutants on the Destabilization of Lipid Bilayers.

Microplastics have been detected in diverse environments, including soil, snowcapped mountains, and even within human organs and blood. These findings have sparked extensive research into the health implications of microplastics for living organisms. Recent studies have shown that microplastics can adsorb onto lipid membranes and induce mechanical stress.